Journal article

Computerised cognitive training to improve cognition including delirium following coronary artery bypass grafting surgery: Protocol for a blinded randomised controlled trial

D Greaves, PJ Psaltis, A Lampit, DHJ Davis, AE Smith, A Bourke, MG Worthington, MJ Valenzuela, HAD Keage

BMJ Open | BMJ PUBLISHING GROUP | Published : 2020

Abstract

Introduction Coronary artery bypass grafting (CABG) surgery is known to improve vascular function and cardiac-related mortality rates; however, it is associated with high rates of postoperative cognitive decline and delirium. Previous attempts to prevent post-CABG cognitive decline using pharmacological and surgical approaches have been largely unsuccessful. Cognitive prehabilitation and rehabilitation are a viable yet untested option for CABG patients. We aim to investigate the effects of preoperative cognitive training on delirium incidence, and preoperative and postoperative cognitive training on cognitive decline at 4 months post-CABG. Methods and analysis This study is a randomised, sin..

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University of Melbourne Researchers

Grants

Awarded by National Health and Medical Research Council


Funding Acknowledgements

DG is supported by the Australian Government Research Training Program Scholarship. HADK is supported by an NHMRC Boosting Dementia Research Leadership Fellowship (GNT1135676) and the National Heart Foundation of Australia Vanguard Grant (101758 - VG 2017). PJP is supported by a National Heart Foundation of Australia Future Leader Fellowship (FLF100412) and an NHMRC Career Development Fellowship (CDF1161506). AL is supported by an NHMRC--ARC Dementia Research Development Fellowship (GNT1108520). DHJD is supported by a Wellcome Trust Intermediate Clinical Fellowship (WT107467). AES is supported by an NHMRC-ARC Dementia Research Development Fellowship (GNT1097397). MJV is supported by an NHMRC Career Development Fellowship (GNT1112813). This study is supported by NMHRC funding from HADK.